The principle of action of methyluracil suppositories

For many men, the problem of prostatitis is familiar firsthand. To get rid of the pathology of the “second heart” of a man (as the representatives of the stronger sex call the prostate gland), all possible means are used.

Methyluracil suppositories for prostatitis are also used in complex therapy. Consider how effective this drug is, how and when it should be used, how the concepts of price and quality correlate.

The drug Methyluracil

The drug under the trade name Methyluracil is registered and produced in Russia. In Soviet times, the drug was popular with bodybuilders , then they were called bodybuilders.

Tablets were considered non-steroidal anabolics. Despite the extremely weak anabolic effect, they contributed to the rapid regeneration of muscles damaged during intense weight training.

Composition and pharmacological action

The full chemical name of the active substance is dioxomethyltetrahydropyrimidine . It belongs to the group of other immunostimulants.

The action of the drug is associated with a positive effect on the exchange of nucleic acids, due to which the processes of regeneration in tissues are accelerated, hematopoiesis of red and white blood sprouts improves, cellular and humoral immunity increases, and anti-inflammatory properties increase.

Influence on metabolic processes consists in anabolic and anti-catabolic effect.

Release form

There are three release forms of Methyluracil :

  • tablets Methyluracil , a dosage of 500 mg of the active substance in packs of 10 tablets;
  • methyluracil ointment 10% in tubes of 25 mg, 1 g of which contains 100 mg of methyluracil ;
  • rectal suppositories of 10 pieces containing methyluracil in 1 suppository 500 mg.

For the manufacture of each of these forms of release, special excipients are used. For tablets, these are starch, talc, povidone and calcium stearate . Methyluracil ointment is based on vaseline and aqueous lanolin. Candles contain polyethylene oxide .

Suppositories Methyluracil – indications for use

The most common use of suppositories with methyluracil was found in proctology. They are successfully prescribed for the following problems of the rectum:

  • proctitis;
  • haemorrhoids;
  • anal itching;
  • anal fissure;
  • erosion of the ano -rectal zone.

It is surprising that despite the absence of such a dosage form as vaginal suppositories, the drug is widely used in gynecology.

The indication for the appointment is:

  • postoperative period after removal of the uterus, polyps, surgical treatment of erosions;
  • colpitis , vaginitis;
  • after an abortion.

With prostatitis , methyluracil suppositories are prescribed in the complex therapy of an acute process to enhance the anti-inflammatory effect, strengthen the immune system, and improve the regeneration of prostate tissues.

To understand why you need to prescribe this drug for prostatitis, let’s briefly get acquainted with the symptoms of the disease. The acute process is characterized by:

  • frequent desire to urinate;
  • the process of urination is accompanied by burning in the urethra and soreness;
  • urination is difficult and does not bring a feeling of satisfaction;
  • pain in the pelvis, lower back, groin.

During the transition to the chronic stage, there is a violation of sexual function, erectile dysfunction, a violation of the quality of the ejaculate, or, more simply, impotence and infertility.

The modern approach to the treatment of prostatitis requires prescribing topical agents simultaneously with antibiotics. The inflamed, edematous tissue of the prostate gland is located in close proximity to the rectum, they are separated only by a thin wall of the intestine.

Therefore, the suppository introduced into the anus quickly penetrates to the focus of inflammation in the shortest way. The anti-inflammatory effect is achieved by improving metabolic processes in the focus, increasing the synthesis of erythrocytes and leukocytes, which also improves the reparative effect in damaged prostate tissues. Reduced swelling facilitates and improves the process of urination.

Method of application and treatment regimen

The method of introducing methyluracil suppositories for the treatment of prostatitis is no different from that for hemorrhoids. The suppository should be administered after a natural bowel movement, in case of delayed stool, a cleansing enema is allowed.

After stool, it is recommended to rinse with water and dry the perianal area. As a precautionary measure, fingernails should be cut short.

The suppository stored in the refrigerator is removed from the package. To facilitate insertion, you can moisten it with water or lubricate the area near the anus with petroleum jelly. It is most convenient to enter it in the position on the side, for right-handed people on the left.

The candle is pushed behind the external sphincter to a depth of 2-4 cm. To prevent the candle from falling out or leaking out, lie on your side for 30-60 minutes.

The treatment regimen involves the introduction of up to 4 suppositories per day against the background of antibiotic therapy. In severe cases, the introduction of 2 suppositories at the same time is allowed.

When acute manifestations subside, the number of injections can be reduced to 1-2 suppositories per day. The course of treatment of acute prostatitis lasts 1-2 weeks.

Methyluracil ointment for prostatitis has not found such widespread use as candles. It is very well suited for the treatment of external hemorrhoids or for accelerating the healing of wounds.

Treatment of chronic inflammation

In chronic prostatitis, tablets and suppositories Methyluracil are used . The duration of treatment with candles is up to 40 days, tablets up to 10 days. Tablets are taken during or after meals, one three times a day, washed down with a moderate amount of clean water.

Candles are administered 3 times a day. With the disappearance of symptoms, it is enough to introduce 1 suppository per day.

The absence of symptoms does not mean a complete cure for chronic prostatitis. The sluggish process is accompanied by a violation of the secretion of prostatic juice, a decrease in the quality of sperm. Therefore, it is important to complete the treatment, and if necessary, repeat after a week break.

The effectiveness of the use of candles

A link to patient reviews helps to judge the effectiveness. Most of them noted a decrease in pain and relief of urination after the first days of treatment . The urge to urinate becomes less frequent. Reduces the burning sensation in the pelvic area.

Side effects occur in rare cases, more often associated with intolerance to the drug.


Contraindications to taking Methyluracil tablets are various forms of leukemia and malignant neoplasms of the bone marrow.
With active granulations in the wound, the use of ointment is not recommended.

For suppositories, a contraindication is idiosyncrasy (individual intolerance) of the main active substance or auxiliary components.

Side effect

While taking the tablets, side effects may develop:

  • allergy;
  • headaches and dizziness;
  • heartburn.

When applied topically, the systemic effect of the drug is not pronounced, therefore, side effects are limited to allergic reactions, burning and itching. If you refuse to use the drug, they pass on their own.

Drug Interactions

The drug is combined with bactericidal drugs, antibiotics.

Simultaneous reception with Cystamin enhances its anti-radiation effect.

Methyluracil and alcohol

Instructions for the use of Methyluracil do not contain direct indications of the inadmissibility of combining alcohol intake during treatment.

Taking into account the fact that alcohol is rapidly absorbed into the blood and Methyluracil , in certain concentrations, is present in the blood even when applied topically, their interaction can lead to an increase and increase in allergic manifestations, as well as to a decrease in the effectiveness of the therapy, due to the provocative effect alcohol on inflamed prostate tissue.

Terms of sale and price

Methyluracil suppositories are available over-the-counter, but this does not mean that the patient can use them on their own, self-medicating.

Treatment is prescribed by a doctor after a thorough examination of the patient.

The price of the drug ranges from 40-60 rubles per pack, which makes it affordable for consumers.


Analogues can be considered drugs that have the same therapeutic effect, but have a different chemical composition.

The following have an immunomodulatory effect:

  • Viferon;
  • Polyoxidonium;
  • Cycloferon;
  • Posterizan ;
  • Immuntil .

There are suppositories containing in addition to methyluracil miramistin , which results in increased bactericidal action. Regeneration is enhanced by:

  • Proctoglivenol ;
  • sea buckthorn;
  • Ichthyol.

Reviews of doctors

Candles with methyluracil for prostatitis are very popular with urologists and andrologists who treat prostate diseases precisely because of their effectiveness and availability in acquisition.

They are successfully used during preparation and in the postoperative period in prostate surgery associated with benign prostatic hyperplasia.

At the same time, the doctor who prescribes suppositories with Methyluracil notes a rapid relief of inflammation, a decrease in prostate edema, an improvement in the passage of urine and an acceleration of the healing of postoperative sutures.


Efficiency in the treatment of prostatitis, ease of use, minimal contraindications and side effects, the absence of negative interactions with other drugs , affordability make methyluracil suppositories the drug of choice in the complex therapy of acute and chronic prostatitis.

Entrust your problem to a specialist doctor and your male health will be restored.

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